- 产品信息
商品描述
靶点-Target
UBP4
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
105kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human UBP4 AA range: 155-205
特异性
This antibody detects endogenous levels of UBP4 at Human/Mouse/Rat
基因名称
USP4 UNP UNPH
蛋白名称
UBP4
别名
Ubiquitin carboxyl-terminal hydrolase 4;Deubiquitinating enzyme 4;Ubiquitin thioesterase 4;Ubiquitin-specific-processing protease 4;Ubiquitous nuclear protein homolog;
Organism-1
Human
基因ID-1
7375
SwissProt-1
Q13107
Organism-2
Mouse
基因ID-2
22258
SwissProt-2
P35123
Organism-3
Rat
基因ID-3
290864
SwissProt-3
B2GUZ1
背景
The protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
细胞定位
Cytoplasm . Nucleus . Shuttles between the nucleus and cytoplasm. Exported to the cytoplasm in a CRM1-dependent manner and recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The relative amounts found in the nucleus and cytoplasm vary according to the cell type. .





