FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CTDP1
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
105kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human CTDP1 AA range: 73-123
特异性
This antibody detects endogenous levels of CTDP1 at Human/Mouse
基因名称
CTDP1 FCP1
蛋白名称
CTDP1
别名
RNA polymerase II subunit A C-terminal domain phosphatase;TFIIF-associating CTD phosphatase;
Organism-1
Human
基因ID-1
9150
SwissProt-1
Q9Y5B0
Organism-2
Mouse
基因ID-2
67655
SwissProt-2
Q7TSG2
背景
This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011],
细胞定位
Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Midbody . Found at centrosomes in prometaphase, at spindle and spindle poles in metaphase and at spindle midzone and midbody in anaphase and telophase-G1 respectively.
