FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
RBM19
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
105kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human RBM19 AA range: 276-326
特异性
This antibody detects endogenous levels of RBM19 at Human/Mouse
基因名称
RBM19 KIAA0682
蛋白名称
RBM19
别名
Probable RNA-binding protein 19;RNA-binding motif protein 19;
Organism-1
Human
基因ID-1
9904
SwissProt-1
Q9Y4C8
Organism-2
Mouse
基因ID-2
74111
SwissProt-2
Q8R3C6
背景
This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009],
细胞定位
Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm . Chromosome . In discrete foci distributed throughout the cytoplasm and nucleoplasm during the 4 to 8 cell stages and the morula stage, but not in the periphery of the nucleolar precursor body (NPB). During blastocyst development, becomes increasingly localized to the nucleolus and less to the cytoplasm. At the late blastocyst stage, localized predominantly in the nucleolus. Localized in the nucleolus during interphase and to the perichromosomal sheath during mitosis. Does not colocalize in the cytoplasm with GW182 in P-bodies. May translocate to the nucleolus upon early embryonic development (By similarity). Colocalizes with NPM1 during interphase. By late prophase, metaphase, anaphase and telophase, associates with the chromosome periphery. By telophase localizes to NPB. .
