FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
LONM
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
105kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human LONM AA range: 398-448
特异性
This antibody detects endogenous levels of LONM at Human/Mouse/Rat
基因名称
LONP1 PRSS15
蛋白名称
LONM
别名
Lon protease homolog, mitochondrial;LONHs;Lon protease-like protein;LONP;Mitochondrial ATP-dependent protease Lon;Serine protease 15;
Organism-1
Human
基因ID-1
9361
SwissProt-1
P36776
Organism-2
Mouse
基因ID-2
74142
SwissProt-2
Q8CGK3
Organism-3
Rat
基因ID-3
170916
SwissProt-3
Q924S5
背景
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013],
细胞定位
Mitochondrion matrix .
