FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DSE
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
105kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human DSE AA range: 164-214
特异性
This antibody detects endogenous levels of DSE at Human/Mouse
基因名称
DSE SART2
蛋白名称
DSE
别名
Dermatan-sulfate epimerase;DS epimerase;Chondroitin-glucuronate 5-epimerase;Squamous cell carcinoma antigen recognized by T-cells 2;SART-2;
Organism-1
Human
基因ID-1
29940
SwissProt-1
Q9UL01
Organism-2
Mouse
基因ID-2
212898
SwissProt-2
Q8BLI4
背景
The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Microsome membrane ; Multi-pass membrane protein .
