FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
VPS45
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
65kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human VPS45 AA range: 470-520
特异性
This antibody detects endogenous levels of VPS45 at Human/Mouse/Rat
基因名称
VPS45 VPS45A VPS45B
蛋白名称
VPS45
别名
Vacuolar protein sorting-associated protein 45;h-VPS45;hlVps45;
Organism-1
Human
基因ID-1
11311
SwissProt-1
Q9NRW7
Organism-2
Mouse
基因ID-2
22365
SwissProt-2
P97390
Organism-3
Rat
基因ID-3
64516
SwissProt-3
O08700
背景
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013],
细胞定位
Golgi apparatus membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Associated with Golgi/endosomal vesicles and the trans-Golgi network. .
