- 产品信息
商品描述
靶点-Target
IL1AP
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
65kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human IL1AP AA range: 213-263
特异性
This antibody detects endogenous levels of IL1AP at Human/Mouse/Rat
基因名称
IL1RAP C3orf13 IL1R3
蛋白名称
IL1AP
别名
Interleukin-1 receptor accessory protein;IL-1 receptor accessory protein;IL-1RAcP;Interleukin-1 receptor 3;IL-1R-3;IL-1R3;
Organism-1
Human
基因ID-1
3556
SwissProt-1
Q9NPH3
Organism-2
Mouse
基因ID-2
16180
SwissProt-2
Q61730
Organism-3
Rat
基因ID-3
25466
SwissProt-3
Q63621
背景
Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Nov 2009],
细胞定位
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.





