FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
EST1
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human EST1 AA range: 7-57
特异性
This antibody detects endogenous levels of EST1 at Human/Mouse
基因名称
CES1 CES2 SES1
蛋白名称
EST1
别名
Liver carboxylesterase 1;Acyl-coenzyme A:cholesterol acyltransferase;ACAT;Brain carboxylesterase hBr1;Carboxylesterase 1;CE-1;hCE-1;Cocaine carboxylesterase;Egasyn;HMSE;Methylumbelliferyl-acetate deacetylase 1;Monocyte/macrophage serine esterase;Retinyl ester hydrolase;REH;Serine esterase 1;Triacylglycerol hydrolase;TGH;
Organism-1
Human
基因ID-1
1066
SwissProt-1
P23141
Organism-2
Mouse
基因ID-2
12623
SwissProt-2
Q8VCC2
背景
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],
细胞定位
Endoplasmic reticulum lumen . Cytoplasm . Lipid droplet . Moves from cytoplasm to lipid droplets upon lipid loading. Associates with lipid droplets independently of triglycerides (TG) content of the droplets and hydrolyzes cholesteryl esters more efficiently from mixed droplets. .
