FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FBXW5
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human FBXW5 AA range: 319-369
特异性
This antibody detects endogenous levels of FBXW5 at Human/Mouse/Rat
基因名称
FBXW5 FBW5 PP3971
蛋白名称
FBXW5
别名
F-box/WD repeat-containing protein 5;F-box and WD-40 domain-containing protein 5;
Organism-1
Human
基因ID-1
54461
SwissProt-1
Q969U6
Organism-2
Mouse
基因ID-2
30839
SwissProt-2
Q9QXW2
Organism-3
Rat
基因ID-3
362081
SwissProt-3
Q4KLI9
背景
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm .
