FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DEAF1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human DEAF1 AA range: 515-565
特异性
This antibody detects endogenous levels of DEAF1 at Human/Mouse/Rat
基因名称
DEAF1 SPN ZMYND5
蛋白名称
DEAF1
别名
Deformed epidermal autoregulatory factor 1 homolog;Nuclear DEAF-1-related transcriptional regulator;NUDR;Suppressin;Zinc finger MYND domain-containing protein 5;
Organism-1
Human
基因ID-1
10522
SwissProt-1
O75398
Organism-2
Mouse
基因ID-2
54006
SwissProt-2
Q9Z1T5
Organism-3
Rat
基因ID-3
83632
SwissProt-3
O88450
背景
This gene encodes a zinc finger domain-containing protein that functions as a regulator of transcription. The encoded proteins binds to its own promoter as well as to that of several target genes. Activity of this protein is important in the regulation of embryonic development. Mutations in this gene have been found in individuals with autosomal dominant mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],
细胞定位
[Isoform 1]: Nucleus. Cytoplasm. Cytoplasmic in non-mucinous colorectal carcinoma. When expressed alone, localized almost exclusively in the nucleus but, when expressed with isoform 4, nuclear expression decreases to 32% and cytoplasmic expression increases by 270%.; [Isoform 2]: Secreted. Secreted in some cell types.; [Isoform 3]: Secreted. Secreted in some cell types.; [Isoform 4]: Cytoplasm. Nucleus. When expressed alone, localizes mainly in the cytoplasm but, when expressed with isoform 1, nuclear localization is enhanced.
