- 产品信息
商品描述
靶点-Target
K2C6B
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human K2C6B AA range: 93-143
特异性
This antibody detects endogenous levels of K2C6B at Human/Mouse
基因名称
KRT6B K6B KRTL1
蛋白名称
K2C6B
别名
Keratin, type II cytoskeletal 6B;Cytokeratin-6B;CK-6B;Keratin-6B;K6B;Type-II keratin Kb10;
Organism-1
Human
基因ID-1
3854
SwissProt-1
P04259
Organism-2
Mouse
SwissProt-2
Q9Z331
背景
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],
细胞定位
keratin filament,extracellular exosome,





