- 产品信息
商品描述
靶点-Target
SPTC2
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human SPTC2 AA range: 273-323
特异性
This antibody detects endogenous levels of SPTC2 at Human/Mouse
基因名称
SPTLC2 KIAA0526 LCB2
蛋白名称
SPTC2
别名
Serine palmitoyltransferase 2;Long chain base biosynthesis protein 2;LCB 2;Long chain base biosynthesis protein 2a;LCB2a;Serine-palmitoyl-CoA transferase 2;SPT 2;
Organism-1
Human
基因ID-1
9517
SwissProt-1
O15270
Organism-2
Mouse
基因ID-2
20773
SwissProt-2
P97363
背景
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011],
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein .





