- 产品信息
商品描述
靶点-Target
OTC
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human OTC AA range: 275-325
特异性
This antibody detects endogenous levels of OTC at Human/Mouse/Rat
基因名称
OTC
蛋白名称
OTC
别名
Ornithine carbamoyltransferase, mitochondrial;Ornithine transcarbamylase;OTCase;
Organism-1
Human
基因ID-1
5009
SwissProt-1
P00480
Organism-2
Mouse
基因ID-2
18416
SwissProt-2
P11725
Organism-3
Rat
基因ID-3
25611
SwissProt-3
P00481
背景
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion matrix .





