FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
KPNA6
反应性
Human,Mouse
应用
WB,IP
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human KPNA6 AA range: 404-454
特异性
This antibody detects endogenous levels of KPNA6 at Human/Mouse
基因名称
KPNA6 IPOA7
蛋白名称
KPNA6
别名
Importin subunit alpha-7;Karyopherin subunit alpha-6;
Organism-1
Human
基因ID-1
23633
SwissProt-1
O60684
Organism-2
Mouse
基因ID-2
16650
SwissProt-2
O35345
背景
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008],
细胞定位
nucleus,nuclear pore,nucleoplasm,cytoplasm,cytosol,membrane,
