- 产品信息
商品描述
靶点-Target
CALCOCO2
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
53kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human CALCOCO2
特异性
This antibody detects endogenous levels of CALCOCO2 at Human/Mouse/Rat
基因名称
CALCOCO2 NDP52
蛋白名称
CALCOCO2
别名
Calcium-binding and coiled-coil domain-containing protein 2;Antigen nuclear dot 52 kDa protein;Nuclear domain 10 protein NDP52;Nuclear domain 10 protein 52;Nuclear dot protein 52;
Organism-1
Human
基因ID-1
10241
SwissProt-1
Q13137
Organism-2
Mouse
基因ID-2
76815
SwissProt-2
A2A6M5
背景
This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a receptor for ubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
细胞定位
Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton . Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein . According to PubMed:7540613, localizes to nuclear dots. According to PubMed:9230084 and PubMed:12869526, it is not a nuclear dot-associated protein but localizes predominantly in the cytoplasm with a coarse-grained distribution preferentially close to the nucleus. .





