FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Mast cell tryptase
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
30kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein AA range: 200-250
特异性
TRYB1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
TPSAB1 TPS1 TPS2 TPSB1
蛋白名称
Tryptase alpha/beta-1 (Tryptase-1) (Tryptase I) (Tryptase alpha-1)
Organism-1
Human
基因ID-1
7177
SwissProt-1
Q15661
Organism-2
Mouse
SwissProt-2
Q02844
Organism-3
Rat
SwissProt-3
P27435
背景
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate gene
细胞定位
Secreted. Released from the secretory granules upon mast cell activation. .
