FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
I23O1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
44kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
I23O1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
IDO1 IDO INDO
蛋白名称
Indoleamine 2,3-dioxygenase 1 (IDO-1) (Indoleamine-pyrrole 2,3-dioxygenase)
Organism-1
Human
基因ID-1
3620
SwissProt-1
P14902
Organism-2
Mouse
SwissProt-2
P28776
Organism-3
Rat
SwissProt-3
Q9ERD9
背景
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011],
细胞定位
Cytoplasm, cytosol .
