KPYR Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2605098

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商品描述
  • 靶点-Target

    KPYR

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    63kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:5000-20000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from part region of human protein at AA range: 510-550

  • 特异性

    KPYR Polyclonal Antibody detects endogenous levels of protein.

  • 基因名称

    PKLR PK1 PKL

  • 蛋白名称

    Pyruvate kinase isozymes R/L (Pyruvate kinase 1) (R-type/L-type pyruvate kinase) (Red cell/liver pyruvate kinase)

  • Organism-1

    Human

  • 基因ID-1

    5313

  • SwissProt-1

    P30613

  • Organism-2

    Mouse

  • SwissProt-2

    P53657

  • Organism-3

    Rat

  • SwissProt-3

    P12928

  • 背景

    The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    cytosol,extracellular exosome,