FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PICK1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
PICK1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
PICK1 PRKCABP
蛋白名称
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Organism-1
Human
基因ID-1
9463
SwissProt-1
Q9NRD5
Organism-2
Mouse
SwissProt-2
Q62083
Organism-3
Rat
SwissProt-3
Q9EP80
背景
protein interacting with PRKCA 1(PICK1) Homo sapiens The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, perinuclear region. Membrane ; Peripheral membrane protein . Membrane ; Lipid-anchor . Cell junction, synapse, postsynaptic density . Cell junction, synapse, synaptosome . Cytoplasm, cytoskeleton . Also membrane-associated, present at excitatory synapses. .
