FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PHLP1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
188kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
PHLP1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
PHLPP1 KIAA0606 PHLPP PLEKHE1 SCOP
蛋白名称
PH domain leucine-rich repeat-containing protein phosphatase 1 (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)
Organism-1
Human
基因ID-1
23239
SwissProt-1
O60346
Organism-2
Mouse
SwissProt-2
Q8CHE4
Organism-3
Rat
SwissProt-3
Q9WTR8
背景
PH domain and leucine rich repeat protein phosphatase 1(PHLPP1) Homo sapiens This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011],
细胞定位
Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. In colorectal cancer tissue, expression is concentrated at the lateral membrane of epithelial cells.; [Isoform 2]: Cell membrane .
