FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ENPP1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
101kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein. AA range: 260-300
特异性
ENPP1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
ENPP1 M6S1 NPPS PC1 PDNP1
蛋白名称
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Membrane component chromosome 6 surface marker 1) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Includes: Alkaline phosphodiesterase I (EC 3.6.1.9)]
Organism-1
Human
基因ID-1
5167
SwissProt-1
P22413
Organism-2
Mouse
SwissProt-2
P06802
Organism-3
Rat
SwissProt-3
Q924C3
背景
This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008],
细胞定位
[Ectonucleotide pyrophosphatase/phosphodiesterase family member 1]: Cell membrane ; Single-pass type II membrane protein. Basolateral cell membrane ; Single-pass type II membrane protein. Targeted to the basolateral membrane in polarized epithelial cells and in hepatocytes, and to matrix vesicles in osteoblasts (PubMed:11598187). In bile duct cells and cancer cells, located to the apical cytoplasmic side (PubMed:11598187). .; [Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form]: Secreted . Secreted following proteolytic cleavage. .
