FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NOX4
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
63kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein AA range:520-578
特异性
NOX4 Polyclonal Antibody detects endogenous levels of protein.
基因名称
NOX4 RENOX
蛋白名称
NADPH oxidase 4 (Kidney oxidase-1) (KOX-1) (Kidney superoxide-producing NADPH oxidase) (Renal NAD(P)H-oxidase)
Organism-1
Human
基因ID-1
50507
SwissProt-1
Q9NPH5
Organism-2
Mouse
SwissProt-2
Q9JHI8
Organism-3
Rat
SwissProt-3
Q924V1
背景
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein . Cell junction, focal adhesion . May localize to plasma membrane and focal adhesions. According to PubMed:15927447, may also localize to the nucleus.; [Isoform 4]: Nucleus . Nucleus, nucleolus .
