FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ILF2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
ILF2 Polyclonal Antibody detects endogenous levels of protein.
基因名称
ILF2 NF45 PRO3063
蛋白名称
Interleukin enhancer-binding factor 2 (Nuclear factor of activated T-cells 45 kDa)
Organism-1
Human
基因ID-1
3608
SwissProt-1
Q12905
Organism-2
Mouse
SwissProt-2
Q9CXY6
Organism-3
Rat
SwissProt-3
Q7TP98
背景
The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Dec 2014],
细胞定位
Nucleus, nucleolus. Cytoplasm . Nucleus . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
