FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DNMT1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
177kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
DNMT1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
DNMT1 AIM CXXC9 DNMT
蛋白名称
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (CXXC-type zinc finger protein 9) (DNA methyltransferase HsaI) (DNA MTase HsaI) (M.HsaI) (MCMT)
Organism-1
Human
基因ID-1
1786
SwissProt-1
P26358
Organism-2
Mouse
SwissProt-2
P13864
Organism-3
Rat
SwissProt-3
Q9Z330
背景
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
细胞定位
Nucleus .
