FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
LRIG1
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
120kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
LRIG1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
LRIG1 LIG1
蛋白名称
Leucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1)
Organism-1
Human
基因ID-1
26018
SwissProt-1
Q96JA1
Organism-2
Mouse
SwissProt-2
P70193
背景
domain:The LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted.,function:Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.,induction:By EGF.,similarity:Contains 17 LRR (leucine-rich) repeats.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4.,tissue specificity:Widely expressed.,
细胞定位
Cell membrane ; Single-pass type I membrane protein .
