FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FKB1A
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
11kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein AA range: 1-50
特异性
FKB1A Polyclonal Antibody detects endogenous levels of protein.
基因名称
FKBP1A FKBP1 FKBP12
蛋白名称
Peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) (12 kDa FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Calstabin-1) (FK506-binding protein 1A) (FKBP-1A) (Immunophilin FKBP12) (Rotamase)
Organism-1
Human
基因ID-1
2280
SwissProt-1
P62942
Organism-2
Mouse
SwissProt-2
P26883
Organism-3
Rat
SwissProt-3
Q62658
背景
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided b
细胞定位
Cytoplasm, cytosol . Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side .
