- 产品信息
商品描述
靶点-Target
ABI3
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
40kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein AA range: 286-336
特异性
ABI3 Polyclonal Antibody detects endogenous levels of protein.
基因名称
ABI3 NESH
蛋白名称
ABI gene family member 3 (New molecule including SH3) (Nesh)
Organism-1
Human
基因ID-1
51225
SwissProt-1
Q9P2A4
Organism-2
Mouse
SwissProt-2
Q8BYZ1
背景
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
细胞定位
Cytoplasm . Colocalizes with PAK2 at leading edge of cells.





