FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SCN8A
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
217kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
SCN8A Polyclonal Antibody detects endogenous levels of protein.
基因名称
SCN8A MED
蛋白名称
Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6)
Organism-1
Human
基因ID-1
6334
SwissProt-1
Q9UQD0
Organism-2
Mouse
SwissProt-2
Q9WTU3
Organism-3
Rat
SwissProt-3
O88420
背景
This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell projection, axon . Mainly localizes to the axon initial segment. .; [Isoform 5]: Cytoplasmic vesicle. Some vesicles are localized adjacent to melanoma invadopodia and macrophage podosomes. Does not localize to the plasma membrane.
