FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
BRD2
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
88kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein AA range: 300-350
特异性
BRD2 Polyclonal Antibody detects endogenous levels of protein.
基因名称
BRD2 KIAA9001 RING3
蛋白名称
Bromodomain-containing protein 2 (O27.1.1) (Really interesting new gene 3 protein)
Organism-1
Human
基因ID-1
6046
SwissProt-1
P25440
Organism-2
Mouse
SwissProt-2
Q7JJ13
Organism-3
Rat
SwissProt-3
Q6MGA9
背景
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010],
细胞定位
Nucleus . Detected on chromatin and nucleosomes.
