- 产品信息
商品描述
靶点-Target
DNMBP
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
173kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein AA range: 940-990
特异性
DNMBP Polyclonal Antibody detects endogenous levels of protein.
基因名称
DNMBP KIAA1010
蛋白名称
Dynamin-binding protein (Scaffold protein Tuba)
Organism-1
Human
基因ID-1
23268
SwissProt-1
Q6XZF7
Organism-2
Mouse
SwissProt-2
Q6TXD4
背景
This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
细胞定位
Cytoplasm . Golgi apparatus, Golgi stack . Cytoplasm, cytoskeleton . Cell junction, synapse . Cell junction . Localizes to the apical junction, colocalizes with TJP1. .





