- 产品信息
商品描述
靶点-Target
CASS4
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
86kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein AA range: 302-352
特异性
CASS4 Polyclonal Antibody detects endogenous levels of protein.
基因名称
CASS4 C20orf32 HEFL
蛋白名称
Cas scaffolding protein family member 4 (HEF-like protein) (HEF1-EFS-p130Cas-like protein) (HEPL)
Organism-1
Human
基因ID-1
57091
SwissProt-1
Q9NQ75
Organism-2
Mouse
SwissProt-2
Q08EC4
背景
alternative products:Experimental confirmation may be lacking for some isoforms,function:Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.,PTM:Phosphorylated on tyrosines by SRC.,similarity:Belongs to the CAS family.,similarity:Contains 1 SH3 domain.,subunit:Interacts (via SH3 domain) with focal adhesion kinase (via C-terminus).,tissue specificity:Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.,
细胞定位
Cytoplasm, cytoskeleton . Cell junction, focal adhesion .





