- 产品信息
商品描述
靶点-Target
NIPA1
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
36kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 111-160
特异性
NIPA1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
NIPA1 SPG6
蛋白名称
Magnesium transporter NIPA1 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 1) (Spastic paraplegia 6 protein)
Organism-1
Human
基因ID-1
123606
SwissProt-1
Q7RTP0
Organism-2
Mouse
SwissProt-2
Q8BHK1
背景
This gene encodes a magnesium transporter that associates with early endosomes and the cell surface in a variety of neuronal and epithelial cells. This protein may play a role in nervous system development and maintenance. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with autosomal dominant spastic paraplegia 6. [provided by RefSeq, Nov 2008],
细胞定位
Cell membrane ; Multi-pass membrane protein . Early endosome . Recruited to the cell membrane in response to low extracellular magnesium. .





