FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
APTX
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
39kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 11-60
特异性
APTX Polyclonal Antibody detects endogenous levels of protein.
基因名称
APTX AXA1
蛋白名称
Aprataxin (Forkhead-associated domain histidine triad-like protein) (FHA-HIT)
Organism-1
Human
基因ID-1
54840
SwissProt-1
Q7Z2E3
Organism-2
Mouse
SwissProt-2
Q7TQC5
Organism-3
Rat
SwissProt-3
Q8K4H4
背景
aprataxin(APTX) Homo sapiens This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Aug 2010],
细胞定位
Nucleus, nucleoplasm . Nucleus, nucleolus . Upon genotoxic stress, colocalizes with XRCC1 at sites of DNA damage (PubMed:15380105). Colocalizes with MDC1 at sites of DNA double-strand breaks (PubMed:20008512). Interaction with NCL is required for nucleolar localization (PubMed:16777843). .; [Isoform 12]: Cytoplasm .
