- 产品信息
商品描述
靶点-Target
ZBP1
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
47kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 21-70
特异性
ZBP1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
ZBP1 C20orf183 DLM1
蛋白名称
Z-DNA-binding protein 1 (Tumor stroma and activated macrophage protein DLM-1)
Organism-1
Human
基因ID-1
81030
SwissProt-1
Q9H171
Organism-2
Mouse
SwissProt-2
Q9QY24
Organism-3
Rat
SwissProt-3
Q8VDA5
背景
This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
细胞定位
Cytoplasm . Nucleus . Mainly cytoplasmic (PubMed:16876127, PubMed:16990255). Accumulates in the nucleus in response to influenza A virus (IAV) infection: senses IAV defective viral genomes RNA in the nucleus (By similarity). .; [Isoform 7]: Cytoplasm . Nucleus . Compared to isoform 1, a higher proportion of this isoform is localized in the nucleus. .





