- 产品信息
商品描述
靶点-Target
FKTN
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 111-160
特异性
FKTN Polyclonal Antibody detects endogenous levels of protein.
基因名称
FKTN FCMD
蛋白名称
Fukutin (Fukuyama-type congenital muscular dystrophy protein)
Organism-1
Human
基因ID-1
2218
SwissProt-1
O75072
Organism-2
Mouse
SwissProt-2
Q8R507
背景
The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2010],
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein . Cytoplasm . Nucleus . In retinal tissue, does not localize with the Golgi apparatus. .





