- 产品信息
商品描述
靶点-Target
SPON1
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
88kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 210-290
特异性
SPON1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
SPON1 KIAA0762 VSGP
蛋白名称
Spondin-1 (F-spondin) (Vascular smooth muscle cell growth-promoting factor)
Organism-1
Human
基因ID-1
10418
SwissProt-1
Q9HCB6
Organism-2
Mouse
SwissProt-2
Q8VCC9
Organism-3
Rat
SwissProt-3
P35446
背景
function:Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell.,similarity:Contains 1 reelin domain.,similarity:Contains 1 spondin domain.,similarity:Contains 6 TSP type-1 domains.,subunit:Binds to the central extracellular domain of APP and inhibits beta-secretase cleavage of APP.,tissue specificity:Highest expression in lung, lower expression in brain, heart, kidney, liver and testis, and lowest expression in pancreas, skeletal muscle and ovary. Not expressed in spleen.,
细胞定位
Secreted, extracellular space, extracellular matrix .





