FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
BACE2
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
56kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 210-290
特异性
BACE2 Polyclonal Antibody detects endogenous levels of protein.
基因名称
BACE2 AEPLC ALP56 ASP21 CDA13 UNQ418/PRO852
蛋白名称
Beta-secretase 2 (Aspartic-like protease 56 kDa) (Aspartyl protease 1) (ASP1) (Asp 1) (Beta-site amyloid precursor protein cleaving enzyme 2) (Beta-site APP cleaving enzyme 2) (Down region aspartic protease) (DRAP) (Memapsin-1) (Membrane-associated aspartic protease 1) (Theta-secretase)
Organism-1
Human
基因ID-1
25825
SwissProt-1
Q9Y5Z0
Organism-2
Mouse
SwissProt-2
Q9JL18
Organism-3
Rat
SwissProt-3
Q6IE75
背景
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Golgi apparatus . Endoplasmic reticulum. Endosome.
