FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
AMGO2
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
57kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 270-350
特异性
AMGO2 Polyclonal Antibody detects endogenous levels of protein.
基因名称
AMIGO2 ALI1
蛋白名称
Amphoterin-induced protein 2 (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA)
Organism-1
Human
基因ID-1
347902
SwissProt-1
Q86SJ2
Organism-2
Mouse
SwissProt-2
Q80ZD9
Organism-3
Rat
SwissProt-3
Q7TNJ4
背景
function:Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.,similarity:Belongs to the immunoglobulin superfamily. AMIGO family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 6 LRR (leucine-rich) repeats.,subcellular location:Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons.,subunit:Binds itself as well as AMIGO1 and AMIGO3.,tissue specificity:Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.,
细胞定位
Cell membrane ; Single-pass type I membrane protein . Nucleus . Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons (By similarity). .
