FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CHIP
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
33kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 160-240
特异性
CHIP Polyclonal Antibody detects endogenous levels of protein.
基因名称
STUB1 CHIP PP1131
蛋白名称
E3 ubiquitin-protein ligase CHIP (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (STIP1 homology and U box-containing protein 1)
Organism-1
Human
基因ID-1
10273
SwissProt-1
Q9UNE7
Organism-2
Mouse
SwissProt-2
Q9WUD1
背景
This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2. [provided by RefSeq, Jun 2014],
细胞定位
Cytoplasm . Nucleus . Translocates to the nucleus in response to inflammatory signals in regulatory T-cells (Treg). .
