- 产品信息
商品描述
靶点-Target
GLRX1
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
11kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 40-120
特异性
GLRX1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
GLRX GRX
蛋白名称
Glutaredoxin-1 (Thioltransferase-1) (TTase-1)
Organism-1
Human
基因ID-1
2745
SwissProt-1
P35754
Organism-2
Mouse
SwissProt-2
Q9QUH0
Organism-3
Rat
SwissProt-3
Q9ESH6
背景
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011],
细胞定位
Cytoplasm.





