FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TPP1
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
61kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
TPP1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
TPP1 CLN2 GIG1 UNQ267/PRO304
蛋白名称
Tripeptidyl-peptidase 1 (TPP-1) (Cell growth-inhibiting gene 1 protein) (Lysosomal pepstatin-insensitive protease) (LPIC) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I)
Organism-1
Human
基因ID-1
1200
SwissProt-1
O14773
Organism-2
Mouse
SwissProt-2
O89023
Organism-3
Rat
SwissProt-3
Q9EQV6
背景
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008],
细胞定位
Lysosome . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
