AMD Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2604445

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商品描述
  • 靶点-Target

    AMD

  • 反应性

    Human,Rat,Mouse

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    107kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:5000-20000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human protein . at AA range: 380-460

  • 特异性

    AMD Polyclonal Antibody detects endogenous levels of protein.

  • 基因名称

    PAM

  • 蛋白名称

    Peptidyl-glycine alpha-amidating monooxygenase (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (PHM) (Peptidylamidoglycolate lyase) (PAL)]

  • Organism-1

    Human

  • 基因ID-1

    5066

  • SwissProt-1

    P19021

  • Organism-2

    Mouse

  • SwissProt-2

    P97467

  • Organism-3

    Rat

  • SwissProt-3

    P14925

  • 背景

    This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],

  • 细胞定位

    Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Secretory granules. .; [Isoform 1]: Membrane; Single-pass type I membrane protein.; [Isoform 2]: Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted. Secreted from secretory granules.; [Isoform 4]: Secreted. Secreted from secretory granules.