- 产品信息
商品描述
靶点-Target
TNR21
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
72kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 430-510
特异性
TNR21 Polyclonal Antibody detects endogenous levels of protein.
基因名称
TNFRSF21 DR6 UNQ437/PRO868
蛋白名称
Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358)
Organism-1
Human
基因ID-1
27242
SwissProt-1
O75509
Organism-2
Mouse
SwissProt-2
Q9EPU5
背景
This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013],
细胞定位
Cell membrane ; Single-pass type I membrane protein .





