FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PPM1B
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
52kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 310-390
特异性
PPM1B Polyclonal Antibody detects endogenous levels of protein.
基因名称
PPM1B PP2CB
蛋白名称
Protein phosphatase 1B (Protein phosphatase 2C isoform beta) (PP2C-beta)
Organism-1
Human
基因ID-1
5495
SwissProt-1
O75688
Organism-2
Mouse
SwissProt-2
P36993
Organism-3
Rat
SwissProt-3
P35815
背景
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytosol . Membrane ; Lipid-anchor . Weakly associates at the membrane and N-myristoylation mediates the membrane localization. .
