- 产品信息
商品描述
靶点-Target
TRY2
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
27kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 40-120
特异性
TRY2 Polyclonal Antibody detects endogenous levels of protein.
基因名称
PRSS2 TRY2 TRYP2
蛋白名称
Trypsin-2 (Anionic trypsinogen) (Serine protease 2) (Trypsin II)
Organism-1
Human
基因ID-1
5645
SwissProt-1
P07478
Organism-2
Mouse
SwissProt-2
P07146
Organism-3
Rat
SwissProt-3
P00763
背景
This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015],
细胞定位
Secreted, extracellular space.





