FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HAVR2
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
33kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
HAVR2 Polyclonal Antibody detects endogenous levels of protein.
基因名称
HAVCR2 TIM3 TIMD3
蛋白名称
Hepatitis A virus cellular receptor 2 (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell membrane protein 3) (TIM-3)
别名
TIM3;CD366;KIM-3;SPTCL;TIMD3;Tim-3;TIMD-3;HAVcr-2
Organism-1
Human
基因ID-1
84868
SwissProt-1
Q8TDQ0
Organism-2
Mouse
SwissProt-2
Q8VIM0
背景
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011],
细胞定位
Membrane ; Single-pass type I membrane protein . Cell junction . Cell membrane . Localizes to the immunological synapse between CD8+ T-cells and target cells. .
