FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PTPRF
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
full lenth:209kD,Mature:140-150kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
PTPRF Polyclonal Antibody detects endogenous levels of protein.
基因名称
PTPRF LAR
蛋白名称
Receptor-type tyrosine-protein phosphatase F (Leukocyte common antigen related) (LAR)
Organism-1
Human
基因ID-1
5792
SwissProt-1
P10586
Organism-2
Mouse
SwissProt-2
A2A8L5
Organism-3
Rat
SwissProt-3
Q64604
背景
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pat
细胞定位
Membrane; Single-pass type I membrane protein.
