FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GPNMB
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
62kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
GPNMB Polyclonal Antibody detects endogenous levels of protein.
基因名称
GPNMB HGFIN NMB UNQ1725/PRO9925
蛋白名称
Transmembrane glycoprotein NMB (Transmembrane glycoprotein HGFIN)
Organism-1
Human
基因ID-1
10457
SwissProt-1
Q14956
Organism-2
Mouse
SwissProt-2
Q99P91
Organism-3
Rat
SwissProt-3
Q6P7C7
背景
glycoprotein nmb(GPNMB) Homo sapiens The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Single-pass type I membrane protein . Melanosome membrane ; Single-pass type I membrane protein . Early endosome membrane ; Single-pass type I membrane protein . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
