FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CYH1
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
43kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
CYH1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
CYTH1 D17S811E PSCD1
蛋白名称
Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1)
Organism-1
Human
基因ID-1
9267
SwissProt-1
Q15438
Organism-2
Mouse
SwissProt-2
Q9QX11
Organism-3
Rat
SwissProt-3
P97694
背景
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
细胞定位
Cell membrane ; Peripheral membrane protein . Cytoplasm, cytosol . Cell junction, tight junction . Cell junction, adherens junction . Colocalized with TJP1 during epithelial polarization. .
