- 产品信息
商品描述
靶点-Target
OSTCN
反应性
Human,Rat,Mouse
应用
WB IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
11kD
推荐稀释比
WB 1:500-2000;IF 1:100-300;ELISA 1:5000-20000;Not yet tested in other applications.
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein AA range: 31-80
特异性
OSTCN Polyclonal Antibody detects endogenous levels of protein.
基因名称
BGLAP
蛋白名称
Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)
Organism-1
Human
基因ID-1
632
SwissProt-1
P02818
Organism-2
Mouse
SwissProt-2
P86546
Organism-3
Rat
SwissProt-3
P04640
背景
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015],
细胞定位
Secreted.





